![]() ![]() ![]() The guidelines have been circulated to all accident and emergency departments in the form of a poster in prose format and we support their use. 9– 11Ĭurrent guidelines for paracetamol poisoning are based on the consensus recommendations of the UK National Poisons Information Service (NPIS), they have also been adopted by the Royal College of Paediatrics and Child Health as a Good Practice Consensus Statement. 8 However, when cases stray from this simple scenario (such as with staggered overdoses, patients with high risk factors for paracetamol poisoning, or late presentation), management decisions are more complex. If the patient has taken a potentially toxic dose of paracetamol, management is guided by the plasma paracetamol concentration treatment with N-acetylcysteine in patients with a toxic plasma paracetamol concentration provides complete protection against paracetamol induced hepatotoxicity. The management of patients who present early (less than 15 hours) after ingestion of a single paracetamol overdose is straightforward. ![]() 1– 6 However, junior doctors' knowledge about the management of paracetamol poisoning is poor. Paracetamol is the commonest drug taken in overdose in the United Kingdom, accounting for 48% of all poisoning admissions to hospital and an estimated 100–200 deaths per year. ![]()
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